Bipolar disorder (acute mania/mixed)
- Stop antidepressant/stimulant contributors
- Severe mania often needs combination therapy
- Lithium or valproate + antipsychotic common
- Antipsychotic monotherapy can also work
- Lithium favored for classic euphoric mania
- Valproate often useful in mixed presentations
- Avoid antidepressant monotherapy
Use at a glance
- Stop antidepressant/stimulant contributors
Treatment options
- Lithium or valproate + antipsychotic common
- Antipsychotic monotherapy can also work
- Lithium favored for classic euphoric mania
- Valproate often useful in mixed presentations
Other treatment options
- Severe mania often needs combination therapy
Safety / pitfalls
- Avoid antidepressant monotherapy
Self-check
- What should be stopped immediately in Bipolar disorder (acute mania/mixed)?
antidepressant/stimulant contributors.
- What is needed for Severe mania in Bipolar disorder (acute mania/mixed)?
combination therapy.
Drugs used for this (11)
All clinical uses · Open the interactive console ↗
