Alzheimer disease (AD)
- Cholinesterase inhibitor in mild–moderate AD
- Donepezil can continue into severe disease
- Memantine for moderate–severe disease
- Anti-amyloid mAb for selected early AD
- confirmed amyloid + MRI monitoring required
- Manage vascular risk, safety + caregiver needs
- Symptomatic drugs do not stop neurodegeneration
Use at a glance
- Cholinesterase inhibitor in mild–moderate AD
Practical pearls
- Donepezil can continue into severe disease
- Memantine for moderate–severe disease
Monitoring / follow-up
- Anti-amyloid mAb for selected early AD
- confirmed amyloid + MRI monitoring required
Safety / pitfalls
- Manage vascular risk, safety + caregiver needs
- Symptomatic drugs do not stop neurodegeneration
Self-check
- What is commonly used for mild–moderate AD?
Cholinesterase inhibitor.
Drugs used for this (5)
All clinical uses · Open the interactive console ↗
