Precursor to metabolite: Alprazolam XR to α-hydroxy alprazolam
Alprazolam XR is converted to α-hydroxy alprazolam by CYP3A4.
The pair
- Alprazolam XR — Extended-release alprazolam for panic disorder; smoother coverage does not remove dependence.
- α-hydroxy alprazolam — Active alprazolam metabolite; low circulating concentrations limit its contribution to clinical effects.
Anything that inhibits or induces CYP3A4 shifts the balance between Alprazolam XR and α-hydroxy alprazolam.
Alprazolam XR · α-hydroxy alprazolam · Open Alprazolam XR in the interactive console ↗