Precursor to metabolite: Trandolapril to Trandolaprilat

Trandolapril is converted to Trandolaprilat by esterase.

Trandolapril mascot — mnemonic cartoon — Trandolapril — mascot

The pair

Trandolapril — Long-acting ACE inhibitor.
Trandolaprilat — Active ACE-inhibiting metabolite of trandolapril; prolonged ACE binding supports sustained blood-pressure lowering.

Trandolapril · Trandolaprilat · Open Trandolapril in the interactive console ↗