Trandolapril
MAVIK
What it isACE inhibitor; hypertension and post-infarction left ventricular dysfunction.
Why this oneA very long half-life gives true once-daily cover.
What limits itCough, hyperkalemia and the hemodynamic creatinine rise. Contraindicated in pregnancy.
FDA-approved for
- hypertension (1996)
⚠ BOXED WARNING
- Fetal toxicity
Cost, est. cash$10–$300/month
Generic entry2006
Classes and tags
Clinical profile
Legacy pregnancy categoryD
Defining liabilityHyperkalemia, kidney injury, angioedema, fetal toxicity and increased lithium exposure.
Active metabolites
Mechanism of action: Trandolapril ballicule
Open Trandolapril in the interactive console ↗
Memory aids: mascots and interaction avatars
Easter/April theme → ACE inhibitor = -pril (aPril)
Bananas in bunches → ↑ serum potassium
