Precursor to metabolite: Risperidone to Paliperidone
Risperidone is converted to Paliperidone by CYP2D6.
The pair
- Risperidone — Widely used atypical; dose-related EPS and the class's greatest prolactin burden.
- Paliperidone — Active metabolite of risperidone; extended-release oral and long-acting injectables.
Anything that inhibits or induces CYP2D6 shifts the balance between Risperidone and Paliperidone.
Risperidone · Paliperidone · Open Risperidone in the interactive console ↗