Precursor to metabolite: Midodrine to Desglymidodrine

Midodrine is converted to Desglymidodrine by systemic hydrolysis.

Midodrine mascot — mnemonic cartoon — Visual mnemonic: Midodrine mascot

The pair

Midodrine — Alpha-1 agonist prodrug for orthostatic hypotension.
Desglymidodrine — Active midodrine metabolite that stimulates peripheral alpha-1 receptors; raises standing blood pressure but can cause supine hypertension.

Midodrine · Desglymidodrine · Open Midodrine in the interactive console ↗