Precursor to metabolite: Clozapine ODT to Norclozapine
Clozapine ODT is converted to Norclozapine by CYP1A2.
The pair
- Clozapine ODT — Orally disintegrating clozapine for patients who cheek or cannot swallow tablets.
- Norclozapine — Active clozapine metabolite; M1 agonist implicated in some clozapine effects.
Anything that inhibits or induces CYP1A2 shifts the balance between Clozapine ODT and Norclozapine.
Clozapine ODT · Norclozapine · Open Clozapine ODT in the interactive console ↗