Precursor to metabolite: Balsalazide to Mesalamine

Balsalazide is converted to Mesalamine by colonic azoreductase.

Balsalazide mascot — mnemonic cartoon — Balsalazide — mascot

Mesalamine mascot — mnemonic cartoon — Mesalamine — mascot

The pair

Balsalazide — Azo prodrug cleaved by colonic bacteria to mesalamine.
Mesalamine — Topically acting 5-ASA for ulcerative colitis; delivery system defines the product.

Balsalazide · Mesalamine · Open Balsalazide in the interactive console ↗