Precursor to metabolite: Alprazolam to α-hydroxyalprazolam
Alprazolam is converted to α-hydroxyalprazolam by CYP3A4.
The pair
- Alprazolam — Short-acting, high-potency benzodiazepine; fast on/off drives dependence and misuse.
- α-hydroxyalprazolam — Active alprazolam metabolite; low circulating concentrations limit its contribution to clinical effects.
Anything that inhibits or induces CYP3A4 shifts the balance between Alprazolam and α-hydroxyalprazolam.
Alprazolam · α-hydroxyalprazolam · Open Alprazolam in the interactive console ↗