VEGFR inhibitor
VEGFR kinase inhibitor
- Blocks VEGFR-1/2/3 signaling → tumor vessels stop sprouting
- Hypertension, proteinuria and impaired wound healing follow from blocking normal endothelial VEGF signaling
- Fruquintinib is VEGFR-selective; the angiokinase card’s agents add FGFR/PDGFR
- Blocks VEGFR-1/2/3 signaling → tumor vessels stop sprouting
- Hypertension, proteinuria and impaired wound healing follow from blocking normal endothelial VEGF signaling
- Fruquintinib is VEGFR-selective; the angiokinase card’s agents add FGFR/PDGFR
Drugs with this mechanism (1)
- Fruquintinib — Selective oral VEGFR angiokinase inhibitor for heavily pretreated metastatic colorectal cancer.
All mechanisms · Open VEGFR inhibitor in the interactive console ↗