V1 antagonist
V1 vasopressin receptor antagonist
- Blocks V1-mediated vasoconstriction
- Also blocks uterine V1 → tocolysis
- Separates the vascular from the antidiuretic actions of vasopressin
Drugs with this mechanism (1)
- Atosiban — Oxytocin/vasopressin antagonist used as a tocolytic (not US).
Self-check
- What does uterine V1 blockade produce?
Tocolysis. - Which listed drug blocks uterine V1 receptors?
Atosiban.
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