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Atosiban

TRACTOCILE

What it isOxytocin and V1a antagonist; tocolysis in preterm labor.

Why this oneIt suppresses contractions with far fewer maternal cardiovascular effects than beta agonists.

What limits itIt delays delivery without clearly improving neonatal outcome. Not US-approved.

FDA-approved for

Off-label

NO BOXED WARNINGS

Principal riskIt delays delivery without clearly improving neonatal outcome

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Atosiban ballicule

Atosiban ballicule: receptor binding, kinetics and half-life diagram

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