SGLT1 inhibitor
Sodium-glucose cotransporter 1 inhibitor
- ↓ glucose absorption and reabsorption
- ↓ postprandial glucose excursion
- Combined SGLT1 and SGLT2 inhibition adds postprandial control
Drugs with this mechanism (1)
- Sotagliflozin — Dual SGLT1/SGLT2 inhibitor for heart failure; intestinal blockade adds diarrhea.
Self-check
- Which glucose excursion does SGLT1 inhibition reduce?
Postprandial. - Which listed drug adds SGLT1 to SGLT2 inhibition?
Sotagliflozin.
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