Toxin sequestrant
- Vast adsorptive surface binds toxins in the gut lumen
- Prevents absorption
- Can interrupt enterohepatic recycling
- Ineffective for metals, alcohols and hydrocarbons
- Aspiration risk in the obtunded
Drugs with this mechanism (1)
- Activated charcoal — Gut adsorbent for selected recent poisonings; ineffective for metals, alcohols, and hydrocarbons.
Self-check
- Does activated charcoal effectively bind alcohols?
No. - What risk is especially important in obtunded patients?
Aspiration.
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