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Activated charcoal

charcoal

What it isNonabsorbed toxin sequestrant that adsorbs many drugs in the gut; selected acute oral poisonings.

Why this oneIt can broadly reduce absorption when given promptly, unlike antidotes that target only one toxin.

What limits it⚑ It does not bind iron, lithium, alcohols, or hydrocarbons; aspiration can be lethal, so withhold if the airway is unprotected.

FDA label

FDA dosingPopulationStartTargetMax
Emergency adsorption of swallowed poisonsAll (as directed by a health professional)20–30 g PO in ≥8 oz liquid ×120–30 g; repeat dose immediately if possibleUndefined

Renal Undefined

Hepatic Undefined

Instructions

Contraindications

Cautions

Pregnancy Undefined

Lactation Undefined

NO BOXED WARNINGS

Principal riskUseless for iron, lithium, alcohols and hydrocarbons

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Activated charcoal ballicule

Activated charcoal ballicule: receptor binding, kinetics and half-life diagram

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