NK3 antagonist

Neurokinin-3 receptor antagonist

Reduces vasomotor symptoms of menopause without hormones
Hepatotoxicity

Drugs with this mechanism (2)

Elinzanetant — Dual NK1/NK3 (neurokinin) antagonist; hormone-free relief for menopausal hot flashes.
Fezolinetant — Oral NK3 antagonist for menopausal hot flashes; avoids estrogen exposure.

All mechanisms · Open the interactive console ↗