NK1 agonist
Neurokinin-1 receptor agonist
- Pain transmission
- Emesis
- Neurogenic inflammation and vasodilation
- Substance P signaling
Drugs with this mechanism (1)
- Substance P — Endogenous NK1 peptide in pain and vomiting pathways.
Self-check
- Which endogenous signal activates NK1 pathways?
Substance P. - Which inflammatory vascular response accompanies NK1 activation?
Neurogenic inflammation and vasodilation.
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