Mucosal barrier

Ulcer-adherent mucosal barrier

Forms an adherent barrier over ulcerated mucosa
Binding is non-selective — other drugs are bound too

Drugs with this mechanism (2)

Bismuth subsalicylate — OTC mucosal protectant and antidiarrheal; salicylate toxicity and interactions still apply.
Sucralfate — Sucrose-aluminum complex that polymerizes on ulcer craters; binds other drugs.

All mechanisms · Open the interactive console ↗