KIT/PDGFRA inhibitor

KIT and PDGFRA kinase inhibitor

Blocks KIT and PDGFRA kinases
Suppresses gastrointestinal stromal tumors, including resistance mutations
A broad-spectrum switch-control inhibitor for later-line GIST

Drugs with this mechanism (1)

Ripretinib — KIT/PDGFRA switch-control inhibitor for heavily pretreated gastrointestinal stromal tumors; alopecia and hand-foot syndrome are common.

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