H4 agonist
H4 histamine receptor agonist
- Located on immune cells
- Chemotaxis and inflammatory modulation, notably in itch
- The most recently discovered histamine receptor
Drugs with this mechanism (1)
- Histamine — Endogenous amine mediating arousal, allergy, and gastric acid.
Self-check
- On which cell population are H4 receptors located?
Immune cells. - Which symptom is notably linked to H4 inflammatory signaling?
Itch.
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