GPR39 agonist
- Couples zinc status to epithelial and neuronal signaling
- One route by which zinc modulates gut and brain function
Drugs with this mechanism (1)
- Zinc — Essential trace mineral and NMDA modulator; OTC, used for colds and Wilson disease.
Self-check
- Which nutrient’s status is coupled to epithelial and neuronal signaling through GPR39?
Zinc. - Which two organ systems are modulated through this zinc-sensing route?
Gut and brain.
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