GlyT1 inhibitor

Glycine transporter 1 reuptake inhibitor

Investigational for schizophrenia to improve cognition and negative symptoms (NMDA hypofunction model)

Drugs with this mechanism (3)

Bitopertin — Investigational GlyT1 inhibitor.
Iclepertin — Investigational GlyT1 inhibitor for schizophrenia cognition.
Sarcosine — A GlyT1 inhibitor studied as a schizophrenia adjunct.

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