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Mechanisms
› GIP agonist
GIP agonist
GIP receptor agonist
Incretin action complementary to GLP-1
Combined GIP/GLP-1 agonism gives greater weight loss
Drugs with this mechanism (3)
Retatrutide
— Investigational triple GIP/GLP-1/glucagon agonist for obesity.
Tirzepatide
— Dual GIP/GLP-1 agonist for diabetes and obesity; exceptional glucose and weight effects.
Tirzepatide (obesity)
— Dual GIP/GLP-1 weight-loss drug; also treats obesity-related sleep apnea.
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