GABA-C agonist
GABA-C receptor agonist
- GABA-A rho receptors, concentrated in retina
- GABA-“see”
- Inhibitory retinal signaling
- brighter blues/greens
- Insensitive to benzodiazepines and baclofen — a pharmacologically distinct receptor
- No clinical applications
Drugs with this mechanism (1)
- Gamma-Aminobutyric Acid — Primary inhibitory CNS neurotransmitter.
Self-check
- Where are GABA-A rho receptors concentrated?
The retina. - Are GABA-A rho receptors sensitive to benzodiazepines or baclofen?
No; they are insensitive to both.
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