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Mechanisms
› EPO receptor agonist
EPO receptor agonist
Stimulates red cell production in renal anemia
Thrombosis and hypertension when hemoglobin is over-corrected
Drugs with this mechanism (2)
Darbepoetin alfa
— Long-acting erythropoietin-receptor agonist; fewer injections than epoetin.
Epoetin alfa
— Recombinant EPO for renal and chemo anemia; do not chase a normal hemoglobin.
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