D5 agonist
D5 dopamine receptor agonist
- The high-affinity D1-family subtype
- Clinically important effects remain uncertain
- Constitutively active in some tissues
Drugs with this mechanism (1)
- Dopamine — Dose-sensitive endogenous catecholamine agonist used IV for selected shock and hypotension.
Self-check
- Which dopamine receptor family contains D5?
The D1 family. - Must D5 receptors always await a ligand to be active?
No—constitutively active in some tissues.
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