D4 agonist
D4 dopamine receptor agonist
- D4 receptors enriched in prefrontal cortex
- Improved working memory (theoretical)
- Clinically important effects remain uncertain
Drugs with this mechanism (1)
- Dopamine — Dose-sensitive endogenous catecholamine agonist used IV for selected shock and hypotension.
Self-check
- Where are D4 receptors enriched?
Prefrontal cortex. - Is D4 agonism’s working-memory benefit established or theoretical?
Theoretical.
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