N-type CCB
N-type calcium channel blocker
- Lamotrigine weakly dampens several presynaptic calcium-channel currents as a secondary effect CCB
Drugs with this mechanism (3)
- Lamotrigine XR — Extended-release lamotrigine for seizures; slow titration reduces serious-rash risk.
- Lamotrigine — Well-tolerated mood stabilizer for bipolar depression; slow titration for rash risk.
- Ziconotide — Intrathecal N-type calcium-channel blocker from cone-snail venom; for refractory pain.
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