TET DNA demethylase cofactor
- Supports active DNA demethylation — an epigenetic role of vitamin C
- Required cofactor for tET DNA demethylase
- Links vitamin C status to gene-expression regulation
Drugs with this mechanism (1)
- Ascorbic acid — Vitamin C; antioxidant and cofactor for collagen and catecholamine synthesis.
Self-check
- Which vitamin supports TET-mediated epigenetic activity?
Vitamin C. - Which broad cellular process links vitamin C status to DNA demethylation?
Gene-expression regulation.
All mechanisms · Open TET DNA demethylase cofactor in the interactive console ↗