Anti-angiogenic antibody
Antibody angiogenic-factor neutralization
- Binds the growth factor beside a vessel sprout, so the sprout never forms
- Bevacizumab and ranibizumab bind VEGF-A; faricimab binds VEGF-A and Ang-2
- Ranibizumab is a Fab fragment with no Fc — the Y is the family symbol, not its anatomy
- Binds the growth factor beside a vessel sprout, so the sprout never forms
- Bevacizumab and ranibizumab bind VEGF-A; faricimab binds VEGF-A and Ang-2
- Ranibizumab is a Fab fragment with no Fc — the Y is the family symbol, not its anatomy
Drugs with this mechanism (3)
- Bevacizumab — VEGF-A antibody that suppresses angiogenesis; bleeding and impaired wound healing shape use.
- Faricimab — Bispecific retinal antibody blocking VEGF-A and angiopoietin-2; intravitreal therapy for macular and retinal edema.
- Ranibizumab — Intravitreal VEGF-A antibody fragment for wet macular degeneration and retinal vascular edema.
All mechanisms · Open Antibody angiogenic-factor neutralization in the interactive console ↗