Alkalinizer
Urinary and systemic alkalinizer
- Ion-traps weak acids (salicylate) in urine → enhanced elimination
- Prevents uric-acid stones by keeping urate ionized and soluble
- Corrects metabolic acidosis
Drugs with this mechanism (2)
- Potassium citrate — Urinary alkalinizer and citrate replacement for recurrent kidney-stone prevention.
- Sodium bicarbonate — Alkalinizing agent; neutralizes gastric acid and ion-traps weak acids in urine.
Self-check
- Why does urine alkalinization enhance salicylate elimination?
Ion-traps the weak acid in urine. - Why can alkalinization prevent uric-acid stones?
Keeps urate ionized and soluble.
All mechanisms · Open Alkalinizer in the interactive console ↗