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Voglibose

BASEN

Voglibose ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Voglibose ballicule

What it isVoglibose is an alpha-glucosidase inhibitor that delays intestinal digestion of complex carbohydrates to blunt postprandial glucose excursions.

Why this oneUsed mainly in Japan and other Asian countries as an adjunct for type 2 diabetes and impaired glucose tolerance.

What limits itIt commonly causes flatulence, abdominal distension, and diarrhea, and is not marketed in the United States.

Voglibose molecular structure (skeletal formula)
Molecular structure: Voglibose

NO BOXED WARNINGS

Principal riskNo FDA boxed warning.

Classes and tags

Clinical profile

Therapeutic safety burden2 / 4
Overdose danger1 / 4
Weight-gain liability0 / 4
Sedation liability1 / 4
QT / Torsades0 / 4
Direct muscarinic antagonism0 / 4

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