Sulindac sulfide
from sulindac
What it isThe active sulfide metabolite of sulindac, a COX inhibitor; arthritis.
Why it mattersReversible reduction from the inactive sulfoxide gives sulindac its long duration.
What it changesStandard NSAID risk once formed. ⛑ Sulindac is the NSAID that does NOT raise lithium, because the parent is inactive.
NO BOXED WARNINGS
Principal riskStandard NSAID GI and renal risk
Classes and tags
Clinical profile
Mechanism of action: Sulindac sulfide ballicule
