Sodium butyrate
butyric acid
“Butter Rick”
What it isSodium salt of butyric acid: a short-chain fatty acid from colonic fiber fermentation and a histone deacetylase inhibitor.
Why this onePrimary colonocyte fuel; the rationale for gut-health supplementation and interest in the fiber-microbiome-butyrate axis.
What limits itSupplement, not an approved drug. Oral butyrate is largely absorbed before reaching the colon; notorious smell and thin clinical evidence.
NO BOXED WARNINGS
Classes and tags
Clinical profile
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Self-check
- Which intestinal cells use butyrate as their primary fuel?
Colonocytes. - Why may oral butyrate fail to reach the colon?
It is largely absorbed beforehand.