Sarin
GB nerve agent
What it isOrganophosphate nerve agent causing irreversible cholinesterase inhibition.
Why this oneIt is the reference agent for the cholinergic toxidrome that atropine and pralidoxime treat.
What limits itAging of the enzyme occurs within minutes, after which pralidoxime cannot work. A chemical weapon with no medical use.
NO BOXED WARNINGS
Principal riskAging of the enzyme occurs within minutes, after which pralidoxime cannot work
Classes and tags
Clinical profile
Mechanism of action: Sarin ballicule
