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Rutin

quercetin rutinoside

What it isFlavonoid glycoside of quercetin used for venous insufficiency.

Why this oneIt is a component of the venoactive preparations used for hemorrhoids and chronic venous disease in Europe.

What limits itEvidence is modest. It is hydrolyzed to quercetin before absorption.

FDA-approved for

Off-label

FDA label

FDA dosingPopulationStartTargetMax
Not stated on label (OTC homeopathic/supplement oral drops)Adults & children ≥12 yr10 drops SL up to TID10 drops SL up to TID10 drops SL TID

Renal Undefined

Hepatic Undefined

Instructions

Pregnancy Undefined

Lactation Undefined

NO BOXED WARNINGS

Principal riskEvidence is modest

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Rutin ballicule

Rutin ballicule: receptor binding, kinetics and half-life diagram

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