Risperidone LAI
RISVAN
Pronunciation: ris-PER-i-doen
“Risp-Van” / “Wristband”
Spooky mascot → antipsychotic
Monthly injection
What it isDepot D2 and 5-HT2A antagonist risperidone; maintenance treatment of schizophrenia.
Why this oneMonthly intramuscular risperidone using in-situ-forming implant technology; no loading regimen and no oral supplementation.
What limits itProlactin elevation, parkinsonism, weight gain, and orthostasis limit use; CYP2D6 inhibitors and CYP3A4 inducers alter exposure.
⚠ BOXED WARNING
- Increased mortality in elderly patients with dementia-related psychosis
Classes and tags
Clinical profile
Legacy pregnancy categoryC
Defining liabilityMetabolic effects, extrapyramidal symptoms/tardive dyskinesia and agent-specific QT or orthostatic risk.
Active metabolites
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Self-check
- RISVAN: What is the injection route?
IM. - RISVAN: Is oral supplementation required?
No.