Promethazine injection
PHENERGAN IM
What it isInjectable H1, muscarinic, and dopamine antagonist; allergy, nausea, and procedural sedation.
Why this oneIt combines antihistamine, antiemetic, and sedative effects in one parenteral agent.
What limits itSevere tissue injury, including gangrene and amputation, can occur regardless of route; deep IM is preferred. It can fatally depress breathing in children under 2.
FDA-approved for
- allergic conditions / nausea / sedation (~1956)
⚠ BOXED WARNINGS
- Respiratory depression in children under 2
- Severe tissue injury including gangrene
Classes and tags
Clinical profile
Mechanism of action: Promethazine injection ballicule
