Pilsicainide
SUNRYTHM
What it isClass IC sodium channel blocker; atrial fibrillation in Japan.
Why this onePure sodium channel blockade with a pill-in-the-pocket role.
What limits itThe CAST proarrhythmia concern applies. Renally cleared; not US-approved.
FDA-approved for
- cardiac arrhythmias (Japan)
Off-label
- atrial fibrillation (approved in Japan)
NO BOXED WARNINGS
Principal riskThe CAST proarrhythmia concern applies
Classes and tags
Clinical profile
Mechanism of action: Pilsicainide ballicule
