Pancuronium
PAVULON
What it isLong-acting competitive muscle nicotinic-receptor antagonist; prolonged surgical paralysis.
Why this oneVagolytic tachycardia distinguishes it from hemodynamically quieter modern neuromuscular blockers.
What limits itRenal accumulation can prolong blockade; use nerve-stimulator monitoring, and remember paralysis provides no sedation or analgesia.
FDA-approved for
- neuromuscular blockade (surgery) (1972)
NO BOXED WARNINGS
Principal riskProlonged block in renal failure; no sedation
Classes and tags
Clinical profile
Mechanism of action: Pancuronium ballicule
