Pronunciation: ox-i-TOE-sin
Mechanism of action: Oxytocin ballicule
Visual mnemonic: Oxytocin mascot
“Ox toes in (love)”
What it isOxytocin- and V1-receptor agonist; labor induction or augmentation and postpartum hemorrhage control.
Why this oneThe standard first-line uterotonic for augmenting labor and preventing or treating postpartum bleeding.
What limits it⚑ Uterine tachysystole can distress the fetus; excessive exposure with dilute fluid can cause water intoxication and hyponatremia.
Molecular structure: Oxytocin
FDA-approved for
⚠ BOXED WARNING
- Not for elective induction of labor
Classes and tags
Clinical profile
Therapeutic safety burden3 / 4
Overdose danger3 / 4
Weight-gain liability0 / 4
Sedation liability0 / 4
QT / Torsades0 / 4
Direct muscarinic antagonism0 / 4
Embryofetal risk3 / 4
Defining liabilityUterine hyperstimulation, fetal hypoxia and water intoxication
Open Oxytocin in the interactive console ↗
Memory aids: interaction avatars
no kinetic interactions
Open Oxytocin in the interactive console ↗
Self-check
- Oxytocin: What uterine effect can distress the fetus?
Tachysystole. - Oxytocin: What can excessive exposure with dilute fluid cause?
Water intoxication and hyponatremia.