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Noribogaine

ibogaine metab.

What it isThe long-lived active metabolite of ibogaine.

Why it mattersIts persistence explains why a single ibogaine dose is reported to suppress craving for weeks.

What it changesIt shares the QT prolongation that makes ibogaine dangerous, and outlasts the parent by days.

FDA-approved for

NO BOXED WARNINGS

Principal riskIt shares the QT prolongation that makes ibogaine dangerous, and outlasts the parent by days

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Noribogaine ballicule

Noribogaine ballicule: receptor binding, kinetics and half-life diagram

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