Methylcobalamin
VITAMIN B12
What it isThe methyl coenzyme form of vitamin B12, cofactor for methionine synthase.
Why it mattersThe form required to remethylate homocysteine, which is why B12 deficiency raises homocysteine.
What it changesNo proven advantage over cyanocobalamin for ordinary repletion, despite marketing to the contrary.
Used for
- vitamin B12 deficiency
- vitamin B12 supplementation
NO BOXED WARNINGS
Principal riskNo proven advantage over cyanocobalamin for correcting deficiency; the difference is largely mar
Classes and tags
Available strengths
- SL tab 1000, 5000 mcg
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Self-check
- Has methylcobalamin proven superior to cyanocobalamin for ordinary repletion?
No. - Which metabolite rises when B12-dependent remethylation fails?
Homocysteine.