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Methylenedioxy­ pyrovalerone

MDPV

What it isSynthetic cathinone and potent dopamine reuptake inhibitor; illicit "bath salts".

Why this oneIt is more potent at DAT than cocaine, which explains the severity of the agitation seen.

What limits itExcited delirium, hyperthermia and rhabdomyolysis. Not detected on routine drug screens.

FDA-approved for

NO BOXED WARNINGS

Principal riskExcited delirium, hyperthermia and rhabdomyolysis

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Methylenedioxy­ pyrovalerone ballicule

Methylenedioxy pyrovalerone ballicule: receptor binding, kinetics and half-life diagram

Open Methylenedioxy­ pyrovalerone in the interactive console ↗