Not available in the U.S.
Lobeglitazone
DUVIE
What it isThiazolidinedione PPAR-gamma agonist that improves peripheral insulin sensitivity.
Why this oneApproved in South Korea (Duvie) for type 2 diabetes, delivering glitazone-class glycemic benefit at low milligram doses.
What limits itShares TZD-class risks of fluid retention, heart failure exacerbation, weight gain and fracture, and is not FDA-approved.
NO BOXED WARNINGS
Principal riskNo FDA boxed warning.
Classes and tags
Clinical profile
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Self-check
- Is lobeglitazone FDA-approved?
No. - What heart-failure risk does lobeglitazone share with TZDs?
Fluid retention and heart-failure exacerbation.