Ketorolac injection
TORADOL IM / IV
Pronunciation: kee-toe-ROEL-ak
“Key to tolerate Torrid”
“The N said... NSAID”
What it isParenteral NSAID for moderately severe acute pain, usually postoperative: 60 mg IM or 30 mg IV once, or 30 mg every 6 h (max 120 mg/day); half that at ≥65 years, <50 kg or with renal impairment.
Why this oneOpioid-level analgesia without respiratory depression or dependence; onset about 30 min, peak 1–2 h; IM half-life 5.3 h (7 h in the elderly).
What limits itFive days total by any route — the boxed warning: GI bleeding, cardiovascular thrombosis, renal failure, bleeding. Contraindicated in CABG surgery, labor and delivery, and epidural or intrathecal use.
FDA-approved for
- moderately severe acute pain, short-term (≤5 days) (1989)
⚠ BOXED WARNINGS
- Cardiovascular thrombotic events
- Gastrointestinal bleeding, ulceration and perforation
- Renal, bleeding and labor risks; 5 days total by any route; not for epidural or intrathecal use
Classes and tags
Clinical profile
Legacy pregnancy categoryMultiple / indication-, trimester- or formulation-dependent
Defining liabilityGI bleeding, kidney injury, hypertension and fluid retention; many agents increase lithium concentrations.
Open Ketorolac injection in the interactive console ↗
Memory aids: interaction avatars
