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Imrecoxib

What it isModerately selective COX-2 inhibitor NSAID.

Why this oneApproved in China for osteoarthritis, designed for less COX-1-related GI toxicity than nonselective NSAIDs while aiming for a milder cardiovascular profile than highly selective coxibs.

What limits itShares NSAID-class cardiovascular thrombotic and GI risks, is metabolized by CYP2C9 and CYP3A4, and is not FDA-approved.

⚠ BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Imrecoxib ballicule

Imrecoxib ballicule: receptor binding, kinetics and half-life diagram

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