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Hypericin

SJW constituent

What it isSt John’s wort pigment and a photosensitiser.

Why this oneIt is the constituent behind the phototoxicity of the herb.

What limits itIt is also the compound most often standardized on the label, though hyperforin drives the interactions.

FDA-approved for

Off-label

NO BOXED WARNINGS

Principal riskPhotosensitivity

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Hypericin ballicule

Hypericin ballicule: receptor binding, kinetics and half-life diagram

Open Hypericin in the interactive console ↗

Memory aids: mascots and interaction avatars

Hypericin mascot mnemonic cartoon
“Hyper rice”
says St John’s wort

Open Hypericin in the interactive console ↗