What it isSt John’s wort pigment and a photosensitiser.
Why this oneIt is the constituent behind the phototoxicity of the herb.
What limits itIt is also the compound most often standardized on the label, though hyperforin drives the interactions.
FDA-approved for
- St John's wort constituent (not approved)
Off-label
- St John's wort constituent studied for depression and as a photosensitizer
Principal riskPhotosensitivity
Classes and tags
Clinical profile
Direct muscarinic antagonism0 / 4
Mechanism of action: Hypericin ballicule
Open Hypericin in the interactive console ↗
Memory aids: mascots and interaction avatars
“Hyper rice”
says St John’s wort
Open Hypericin in the interactive console ↗