Hydroxyzine IM
VISTARIL IM
What it isInjectable H1 antagonist with antimuscarinic, alpha-1, and serotonin blockade; acute anxiety, nausea, and perioperative sedation.
Why this oneThe non-controlled acute anxiolytic on agitation order sets; IM only among the parenteral routes.
What limits itIM ONLY — SC, IV, and intra-arterial injection cause tissue damage (hemolysis with IV). QTc caution at high doses.
FDA-approved for
- anxiety/tension (acute) (~1958)
- nausea/vomiting; pre/post-op adjunct (~1958)
NO BOXED WARNINGS
Principal riskSedation and anticholinergic burden; QT at high dose
Classes and tags
Clinical profile
Active metabolites
Mechanism of action: Hydroxyzine IM ballicule
